Pyoderma gangrenosum associated with rheumatoid arthritis mimicking vasculitis

Pyoderma gangrenosum is a rare neutrophilic dermatosis characterized by painful, rapidly progressing necrotic ulcers. Although PG has been reported in association with various autoimmune diseases, its coexistence rheumatoid arthritis (RA) mimicking vasculitis uncommon. We present case report of 75-year-old female longstanding history RA who developed ulcerative skin lesions that initially presented as vasculitis. She new-onset lesion on the lower extremity, accompanied malaise. Physical examination revealed asymmetric, deep ulcers undermined borders. Laboratory investigations showed elevated acute phase reactants and negative factor. Skin biopsy demonstrated infiltration, confirming diagnosis PG. Further investigations, including imaging studies vasculitis-specific laboratory tests, were negative, ruling out The patient was managed systemic corticosteroids immunosuppressive therapy, resulting significant improvement lesions. This highlights importance considering potential differential patients presenting resembling